人 NEK2 (NM_002497) cDNA克隆

基本信息

Accession: NM_002497
基因名称: NEK2
基因别名: NLK1; NEK2A; HsPK21
基因描述: Homo sapiens NIMA-related kinase 2 (NEK2), transcript variant 1, mRNA.
种属: Human
CDS区长度: 1338 (查看编码区序列)
翻译后氨基酸长度: 445 (查看氨基酸序列)
Transcript Variant: This variant (1) represents the predominant transcript, and encodes the longest isoform (1, also known as NEK2A). The C-terminus (aa 399-445) of this isoform was shown to be responsible for its nucleolar localization (PMID:15161910). Isoforms 1 and 2 (which differ at the C-terminus) have also been reported to exhibit distinct pattern of expression during mitosis (PMID:11742531).

订购信息

产品编号 产品名称 载体 规格 价格
G120006 人 NEK2 (NM_002497) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 NEK2 (NM_002497) cDNA克隆 transcript variant 1
人 NEK2 (NM_001204183) cDNA克隆 transcript variant 2
人 NEK2 (NM_001204182) cDNA克隆 transcript variant 3

基因简介

This gene encodes a serine/threonine-protein kinase that is involved in mitotic regulation. This protein is localized to the centrosome, and undetectable during G1 phase, but accumulates progressively throughout the S phase, reaching maximal levels in late G2 phase. Alternatively spliced transcript variants encoding different isoforms with distinct C-termini have been noted for this gene. [provided by RefSeq, Feb 2011]

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