人 NEK3 (NM_002498) cDNA克隆

Accession: NM_002498
基因名称: NEK3
基因别名: HSPK36
基因描述: Homo sapiens NIMA-related kinase 3 (NEK3), transcript variant 1, mRNA.
种属: Human
CDS区长度: 1521 (查看编码区序列)
翻译后氨基酸长度: 506 (查看氨基酸序列)
Transcript Variant: This variant (1) represents the longest transcript. Variants 1 and 2 encode the same isoform (a).
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G111852 人 NEK3 (NM_002498) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a member of the NimA (never in mitosis A) family of serine/threonine protein kinases. The encoded protein differs from other NimA family members in that it is not cell cycle regulated and is found primarily in the cytoplasm. The kinase is activated by prolactin stimulation, leading to phosphorylation of VAV2 guanine nucleotide exchange factor, paxillin, and activation of the RAC1 GTPase. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2009]