人 PIK3R1 (NM_181504) cDNA克隆

基本信息

Accession: NM_181504
基因名称: PIK3R1
基因别名: p85; AGM7; GRB1; p85-ALPHA
基因描述: Homo sapiens phosphoinositide-3-kinase, regulatory subunit 1 (alpha) (PIK3R1), transcript variant 2, mRNA.
种属: Human
CDS区长度: 1365 (查看编码区序列)
翻译后氨基酸长度: 454 (查看氨基酸序列)
Transcript Variant: This variant (2) uses an alternate in-frame exon in the 5' coding region, compared to variant 1. The encoded isoform (2) has a distinct N-terminus, compared to isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G119017 人 PIK3R1 (NM_181504) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 PIK3R1 (NM_181523) cDNA克隆 transcript variant 1
人 PIK3R1 (NM_181504) cDNA克隆 transcript variant 2
人 PIK3R1 (NM_181524) cDNA克隆 transcript variant 3
人 PIK3R1 (NM_001242466) cDNA克隆 transcript variant 4

基因简介

Phosphatidylinositol 3-kinase phosphorylates the inositol ring of phosphatidylinositol at the 3-prime position. The enzyme comprises a 110 kD catalytic subunit and a regulatory subunit of either 85, 55, or 50 kD. This gene encodes the 85 kD regulatory subunit. Phosphatidylinositol 3-kinase plays an important role in the metabolic actions of insulin, and a mutation in this gene has been associated with insulin resistance. Alternative splicing of this gene results in four transcript variants encoding different isoforms. [provided by RefSeq, Jun 2011]

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