人 PIK3CB (NM_001256045) cDNA克隆

基本信息

Accession: NM_001256045
基因名称: PIK3CB
基因别名: PI3K; PIK3C1; P110BETA; PI3KBETA
基因描述: Homo sapiens phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta (PIK3CB), transcript variant 2, mRNA.
种属: Human
CDS区长度: 1749 (查看编码区序列)
翻译后氨基酸长度: 582 (查看氨基酸序列)
Transcript Variant: This variant (2) differs in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at a downstream AUG compared to variant 1. The resulting protein (isoform 2) is shorter and has a distinct N-terminus compared to isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G124594 人 PIK3CB (NM_001256045) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 PIK3CB (NM_006219) cDNA克隆 transcript variant 1
人 PIK3CB (NM_001256045) cDNA克隆 transcript variant 2

基因简介

This gene encodes an isoform of the catalytic subunit of phosphoinositide 3-kinase (PI3K). These kinases are important in signaling pathways involving receptors on the outer membrane of eukaryotic cells and are named for their catalytic subunit. The encoded protein is the catalytic subunit for PI3Kbeta (PI3KB). PI3KB has been shown to be part of the activation pathway in neutrophils which have bound immune complexes at sites of injury or infection. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2011]

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