人 TREX1 (NM_007248) cDNA克隆

基本信息

Accession: NM_007248
基因名称: TREX1
基因别名: CRV; AGS1; DRN3; HERNS
基因描述: Homo sapiens three prime repair exonuclease 1 (TREX1), transcript variant 5, mRNA.
种属: Human
CDS区长度: 915 (查看编码区序列)
翻译后氨基酸长度: 304 (查看氨基酸序列)
Transcript Variant: This variant (5) uses an alternate splice site in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at a downstream in-frame start codon, compared to variant 1. The resulting isoform (c) has a shorter N-terminus, compared to isoform a.

订购信息

产品编号 产品名称 载体 规格 价格
G117826 人 TREX1 (NM_007248) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 TREX1 (NM_016381) cDNA克隆 transcript variant 1
人 TREX1 (NM_033629) cDNA克隆 transcript variant 4
人 TREX1 (NM_007248) cDNA克隆 transcript variant 5

基因简介

This gene encodes a nuclear protein with 3' exonuclease activity. The encoded protein may play a role in DNA repair and serve as a proofreading function for DNA polymerase. Mutations in this gene result in Aicardi-Goutieres syndrome, chilblain lupus, Cree encephalitis, and other diseases of the immune system. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2012]

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