人 TREX1 (NM_016381) cDNA克隆

Accession: NM_016381
基因名称: TREX1
基因别名: CRV; AGS1; DRN3; HERNS
基因描述: Homo sapiens three prime repair exonuclease 1 (TREX1), transcript variant 1, mRNA.
种属: Human
CDS区长度: 1110 (查看编码区序列)
翻译后氨基酸长度: 369 (查看氨基酸序列)
Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (a).
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G117824 人 TREX1 (NM_016381) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a nuclear protein with 3' exonuclease activity. The encoded protein may play a role in DNA repair and serve as a proofreading function for DNA polymerase. Mutations in this gene result in Aicardi-Goutieres syndrome, chilblain lupus, Cree encephalitis, and other diseases of the immune system. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2012]