人 GNLY (NM_012483) cDNA克隆

Accession: NM_012483
基因名称: GNLY
基因别名: 519; LAG2; NKG5; LAG-2; D2S69E; TLA519
基因描述: Homo sapiens granulysin (GNLY), transcript variant 519, mRNA.
种属: Human
CDS区长度: 393 (查看编码区序列)
翻译后氨基酸长度: 130 (查看氨基酸序列)
Transcript Variant: This variant (519) contains an additional segment in the coding region compared to variant NKG5. The resulting isoform (isoform 519 ) contains a shorter and distinct N-terminus compared to isoform NKG5.
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G117686 人 GNLY (NM_012483) cDNA克隆 pDONR223 2ug质粒 点击询价

The product of this gene is a member of the saposin-like protein (SAPLIP) family and is located in the cytotoxic granules of T cells, which are released upon antigen stimulation. This protein is present in cytotoxic granules of cytotoxic T lymphocytes and natural killer cells, and it has antimicrobial activity against M. tuberculosis and other organisms. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]