人 GNLY (NM_006433) cDNA克隆

Accession: NM_006433
基因名称: GNLY
基因别名: 519; LAG2; NKG5; LAG-2; D2S69E; TLA519
基因描述: Homo sapiens granulysin (GNLY), transcript variant NKG5, mRNA.
种属: Human
CDS区长度: 438 (查看编码区序列)
翻译后氨基酸长度: 145 (查看氨基酸序列)
Transcript Variant: This variant, NKG5, represents the shorter transcript, but encodes the longer isoform, isoform NKG5.
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G117685 人 GNLY (NM_006433) cDNA克隆 pDONR223 2ug质粒 点击询价

The product of this gene is a member of the saposin-like protein (SAPLIP) family and is located in the cytotoxic granules of T cells, which are released upon antigen stimulation. This protein is present in cytotoxic granules of cytotoxic T lymphocytes and natural killer cells, and it has antimicrobial activity against M. tuberculosis and other organisms. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]