人 CDKN3 (NM_005192) cDNA克隆

Accession: NM_005192
基因名称: CDKN3
基因别名: KAP; CDI1; CIP2; KAP1
基因描述: Homo sapiens cyclin-dependent kinase inhibitor 3 (CDKN3), transcript variant 1, mRNA.
种属: Human
CDS区长度: 639 (查看编码区序列)
翻译后氨基酸长度: 212 (查看氨基酸序列)
Transcript Variant: This variant (1) encodes the longer isoform (1).
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G117168 人 CDKN3 (NM_005192) cDNA克隆 pDONR223 2ug质粒 点击询价

The protein encoded by this gene belongs to the dual specificity protein phosphatase family. It was identified as a cyclin-dependent kinase inhibitor, and has been shown to interact with, and dephosphorylate CDK2 kinase, thus prevent the activation of CDK2 kinase. This gene was reported to be deleted, mutated, or overexpressed in several kinds of cancers. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]