人 UBE2K (NM_001111112) cDNA克隆

基本信息

Accession: NM_001111112
基因名称: UBE2K
基因别名: LIG; HIP2; HYPG; UBC1; E2-25K
基因描述: Homo sapiens ubiquitin-conjugating enzyme E2K (UBE2K), transcript variant 2, mRNA.
种属: Human
CDS区长度: 474 (查看编码区序列)
翻译后氨基酸长度: 157 (查看氨基酸序列)
Transcript Variant: This variant (2) lacks an alternate in-frame exon in the 3' coding region, compared to variant 1, resulting in a shorter protein (isoform 2), compared to isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G116545 人 UBE2K (NM_001111112) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 UBE2K (NM_005339) cDNA克隆 transcript variant 1
人 UBE2K (NM_001111112) cDNA克隆 transcript variant 2
人 UBE2K (NM_001111113) cDNA克隆 transcript variant 3

基因简介

The protein encoded by this gene belongs to the ubiquitin-conjugating enzyme family. This protein interacts with RING finger proteins, and it can ubiquitinate huntingtin, the gene product for Huntington's disease. Known functions for this protein include a role in aggregate formation of expanded polyglutamine proteins and the suppression of apoptosis in polyglutamine diseases, a role in the dislocation of newly synthesized MHC class I heavy chains from the endoplasmic reticulum, and involvement in foam cell formation. Multiple transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]

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