人 PROM1 (NM_006017) cDNA克隆

Accession: NM_006017
基因名称: PROM1
基因别名: RP41; AC133; CD133; MCDR2; STGD4; CORD12; PROML1; MSTP061
基因描述: Homo sapiens prominin 1 (PROM1), transcript variant 1, mRNA.
种属: Human
CDS区长度: 2598 (查看编码区序列)
翻译后氨基酸长度: 865 (查看氨基酸序列)
Transcript Variant: This variant (1) represents the longest isoform (1), also known as s2. The full structure of the 5' UTR for this variant has not been determined.
产品编号 产品名称 载体 规格 价格
G113937 人 PROM1 (NM_006017) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a pentaspan transmembrane glycoprotein. The protein localizes to membrane protrusions and is often expressed on adult stem cells, where it is thought to function in maintaining stem cell properties by suppressing differentiation. Mutations in this gene have been shown to result in retinitis pigmentosa and Stargardt disease. Expression of this gene is also associated with several types of cancer. This gene is expressed from at least five alternative promoters that are expressed in a tissue-dependent manner. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]