人 PROM1 (NM_001145847) cDNA克隆

基本信息

Accession: NM_001145847
基因名称: PROM1
基因别名: RP41; AC133; CD133; MCDR2; STGD4; CORD12; PROML1; MSTP061
基因描述: Homo sapiens prominin 1 (PROM1), transcript variant 2, mRNA.
种属: Human
CDS区长度: 2571 (查看编码区序列)
翻译后氨基酸长度: 856 (查看氨基酸序列)
Transcript Variant: This variant (2) represents one of several alternative promoters and 5' UTRs, and lacks an alternative in-frame exon in the 5' coding region, compared to variant 1. The resulting isoform (2), also known as s1, lacks a 9 aa segment near the N-terminus, compared to isoform 1. Both variants 2 and 3 encode the same isoform.

订购信息

产品编号 产品名称 载体 规格 价格
G113931 人 PROM1 (NM_001145847) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 PROM1 (NM_006017) cDNA克隆 transcript variant 1
人 PROM1 (NM_001145847) cDNA克隆 transcript variant 2
人 PROM1 (NM_001145848) cDNA克隆 transcript variant 3
人 PROM1 (NM_001145852) cDNA克隆 transcript variant 4
人 PROM1 (NM_001145851) cDNA克隆 transcript variant 5
人 PROM1 (NM_001145850) cDNA克隆 transcript variant 6
人 PROM1 (NM_001145849) cDNA克隆 transcript variant 7

基因简介

This gene encodes a pentaspan transmembrane glycoprotein. The protein localizes to membrane protrusions and is often expressed on adult stem cells, where it is thought to function in maintaining stem cell properties by suppressing differentiation. Mutations in this gene have been shown to result in retinitis pigmentosa and Stargardt disease. Expression of this gene is also associated with several types of cancer. This gene is expressed from at least five alternative promoters that are expressed in a tissue-dependent manner. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]

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