人 BIRC2 (NM_001256166) cDNA克隆

基本信息

Accession: NM_001256166
基因名称: BIRC2
基因别名: API1; MIHB; HIAP2; RNF48; cIAP1; Hiap-2; c-IAP1
基因描述: Homo sapiens baculoviral IAP repeat containing 2 (BIRC2), transcript variant 3, mRNA.
种属: Human
CDS区长度: 1710 (查看编码区序列)
翻译后氨基酸长度: 569 (查看氨基酸序列)
Transcript Variant: This variant (3) has an alternate splice site in the 5' region, which results in a downstream AUG start codon, compared to variant 1. The resulting isoform (2) is shorter at the N-terminus, compared to isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G113715 人 BIRC2 (NM_001256166) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 BIRC2 (NM_001166) cDNA克隆 transcript variant 1
人 BIRC2 (NM_001256163) cDNA克隆 transcript variant 2
人 BIRC2 (NM_001256166) cDNA克隆 transcript variant 3

基因简介

The protein encoded by this gene is a member of a family of proteins that inhibits apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. This encoded protein inhibits apoptosis induced by serum deprivation and menadione, a potent inducer of free radicals. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]

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