人 BIRC2 (NM_001256163) cDNA克隆

Accession: NM_001256163
基因名称: BIRC2
基因别名: API1; MIHB; HIAP2; RNF48; cIAP1; Hiap-2; c-IAP1
基因描述: Homo sapiens baculoviral IAP repeat containing 2 (BIRC2), transcript variant 2, mRNA.
种属: Human
CDS区长度: 1857 (查看编码区序列)
翻译后氨基酸长度: 618 (查看氨基酸序列)
Transcript Variant: This variant (2) differs in the 5' UTR, compared to variant 1. Variants 1 and 2 encode the same isoform (1).
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G113714 人 BIRC2 (NM_001256163) cDNA克隆 pDONR223 2ug质粒 点击询价

The protein encoded by this gene is a member of a family of proteins that inhibits apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. This encoded protein inhibits apoptosis induced by serum deprivation and menadione, a potent inducer of free radicals. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]