人 PDE1C (NM_001191059) cDNA克隆

基本信息

Accession: NM_001191059
基因名称: PDE1C
基因别名: Hcam3
基因描述: Homo sapiens phosphodiesterase 1C, calmodulin-dependent 70kDa (PDE1C), transcript variant 5, mRNA.
种属: Human
CDS区长度: 2130 (查看编码区序列)
翻译后氨基酸长度: 709 (查看氨基酸序列)
Transcript Variant: This variant (5) differs in the 5' UTR and has multiple coding region differences, compared to variant 3. These differences result in an isoform (2) with a distinct N-terminus, compared to isoform 3. Variants 2 and 5 encode the same protein. Isoform 2 is also known as HCam-3A.

订购信息

产品编号 产品名称 载体 规格 价格
G113669 人 PDE1C (NM_001191059) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 PDE1C (NM_001191056) cDNA克隆 transcript variant 1
人 PDE1C (NM_001191057) cDNA克隆 transcript variant 2
人 PDE1C (NM_001191058) cDNA克隆 transcript variant 3
人 PDE1C (NM_005020) cDNA克隆 transcript variant 4
人 PDE1C (NM_001191059) cDNA克隆 transcript variant 5

基因简介

Cyclic nucleotide phosphodiesterases (PDEs) catalyze hydrolysis of the cyclic nucleotides cAMP and cGMP to the corresponding nucleoside 5-prime-monophosphates. Mammalian PDEs have been classified into several families based on their biochemical properties. Members of the PDE1 family, such as PDE1C, are calmodulin (see MIM 114180)-dependent PDEs (CaM-PDEs) that are stimulated by a calcium-calmodulin complex (Repaske et al., 1992 [PubMed 1326532]).[supplied by OMIM, Oct 2009]

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