人 PDE1C (NM_001191058) cDNA克隆

Accession: NM_001191058
基因名称: PDE1C
基因别名: Hcam3
基因描述: Homo sapiens phosphodiesterase 1C, calmodulin-dependent 70kDa (PDE1C), transcript variant 3, mRNA.
种属: Human
CDS区长度: 2310 (查看编码区序列)
翻译后氨基酸长度: 769 (查看氨基酸序列)
Transcript Variant: This variant (3) encodes the longest isoform (3).
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G113668 人 PDE1C (NM_001191058) cDNA克隆 pDONR223 2ug质粒 点击询价

Cyclic nucleotide phosphodiesterases (PDEs) catalyze hydrolysis of the cyclic nucleotides cAMP and cGMP to the corresponding nucleoside 5-prime-monophosphates. Mammalian PDEs have been classified into several families based on their biochemical properties. Members of the PDE1 family, such as PDE1C, are calmodulin (see MIM 114180)-dependent PDEs (CaM-PDEs) that are stimulated by a calcium-calmodulin complex (Repaske et al., 1992 [PubMed 1326532]).[supplied by OMIM, Oct 2009]