人 PTPRA (NM_080840) cDNA克隆

基本信息

Accession: NM_080840
基因名称: PTPRA
基因别名: LRP; HLPR; PTPA; HEPTP; HPTPA; RPTPA; PTPRL2; HPTPalpha; R-PTP-alpha
基因描述: Homo sapiens protein tyrosine phosphatase, receptor type, A (PTPRA), transcript variant 2, mRNA.
种属: Human
CDS区长度: 2382 (查看编码区序列)
翻译后氨基酸长度: 793 (查看氨基酸序列)
Transcript Variant: This variant (2) contains an alternate 5' UTR exon, and lacks an internal coding exon, when compared to variant 1. The resulting isoform (2) lacks a 9 aa internal segment, as compared to isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G112891 人 PTPRA (NM_080840) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 PTPRA (NM_002836) cDNA克隆 transcript variant 1
人 PTPRA (NM_080840) cDNA克隆 transcript variant 2
人 PTPRA (NM_080841) cDNA克隆 transcript variant 3

基因简介

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. This PTP has been shown to dephosphorylate and activate Src family tyrosine kinases, and is implicated in the regulation of integrin signaling, cell adhesion and proliferation. Three alternatively spliced variants of this gene, which encode two distinct isoforms, have been reported. [provided by RefSeq, Jul 2008]

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