人 PTPRA (NM_002836) cDNA克隆

Accession: NM_002836
基因名称: PTPRA
基因别名: LRP; HLPR; PTPA; HEPTP; HPTPA; RPTPA; PTPRL2; HPTPalpha; R-PTP-alpha
基因描述: Homo sapiens protein tyrosine phosphatase, receptor type, A (PTPRA), transcript variant 1, mRNA.
种属: Human
CDS区长度: 2409 (查看编码区序列)
翻译后氨基酸长度: 802 (查看氨基酸序列)
Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoform (1).
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G112890 人 PTPRA (NM_002836) cDNA克隆 pDONR223 2ug质粒 点击询价

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. This PTP has been shown to dephosphorylate and activate Src family tyrosine kinases, and is implicated in the regulation of integrin signaling, cell adhesion and proliferation. Three alternatively spliced variants of this gene, which encode two distinct isoforms, have been reported. [provided by RefSeq, Jul 2008]