人 PAK6 (NM_001128628) cDNA克隆

基本信息

Accession: NM_001128628
基因名称: PAK6
基因别名: PAK5
基因描述: Homo sapiens p21 protein (Cdc42/Rac)-activated kinase 6 (PAK6), transcript variant 2, mRNA.
种属: Human
CDS区长度: 2046 (查看编码区序列)
翻译后氨基酸长度: 681 (查看氨基酸序列)
Transcript Variant: This variant (2) differs in the 5' UTR, compared to variant 1. Variants 1, 2, 3, and 4 encode the same isoform (1).

订购信息

产品编号 产品名称 载体 规格 价格
G112631 人 PAK6 (NM_001128628) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 PAK6 (NM_020168) cDNA克隆 transcript variant 1
人 PAK6 (NM_001128628) cDNA克隆 transcript variant 2
人 PAK6 (NM_001128629) cDNA克隆 transcript variant 3
人 PAK6 (NM_001276717) cDNA克隆 transcript variant 4
人 PAK6 (NM_001276718) cDNA克隆 transcript variant 5

基因简介

This gene encodes a member of a family of p21-stimulated serine/threonine protein kinases, which contain an amino-terminal Cdc42/Rac interactive binding (CRIB) domain and a carboxyl-terminal kinase domain. These kinases function in a number of cellular processes, including cytoskeleton rearrangement, apoptosis, and the mitogen-activated protein (MAP) kinase signaling pathway. The protein encoded by this gene interacts with androgen receptor (AR) and translocates to the nucleus, where it is involved in transcriptional regulation. Changes in expression of this gene have been linked to prostate cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2013]

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