人 PAK4 (NM_001014834) cDNA克隆

基本信息

Accession: NM_001014834
基因名称: PAK4
基因描述: Homo sapiens p21 protein (Cdc42/Rac)-activated kinase 4 (PAK4), transcript variant 5, mRNA.
种属: Human
CDS区长度: 1317 (查看编码区序列)
翻译后氨基酸长度: 438 (查看氨基酸序列)
Transcript Variant: This variant (5) lacks an exon in the 5' UTR and an in-frame exon in the coding region, as compared to variant 1. The encoded isoform (2) thus lacks an internal segment, as compared to isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G102318 人 PAK4 (NM_001014834) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 PAK4 (NM_005884) cDNA克隆 transcript variant 1
人 PAK4 (NM_001014831) cDNA克隆 transcript variant 2
人 PAK4 (NM_001014832) cDNA克隆 transcript variant 3
人 PAK4 (NM_001014835) cDNA克隆 transcript variant 4
人 PAK4 (NM_001014834) cDNA克隆 transcript variant 5

基因简介

PAK proteins, a family of serine/threonine p21-activating kinases, include PAK1, PAK2, PAK3 and PAK4. PAK proteins are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. They serve as targets for the small GTP binding proteins Cdc42 and Rac and have been implicated in a wide range of biological activities. PAK4 interacts specifically with the GTP-bound form of Cdc42Hs and weakly activates the JNK family of MAP kinases. PAK4 is a mediator of filopodia formation and may play a role in the reorganization of the actin cytoskeleton. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

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