人 PDK1 (NM_002610) cDNA克隆

基本信息

Accession: NM_002610
基因名称: PDK1
基因描述: Homo sapiens pyruvate dehydrogenase kinase, isozyme 1 (PDK1), transcript variant 2, mRNA.
种属: Human
CDS区长度: 1311 (查看编码区序列)
翻译后氨基酸长度: 436 (查看氨基酸序列)
Transcript Variant: This variant (2) lacks an in-frame exon in the coding region, compared to variant 1. The resulting isoform (2) lacks an internal segment, compared to isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G111006 人 PDK1 (NM_002610) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 PDK1 (NM_001278549) cDNA克隆 transcript variant 1
人 PDK1 (NM_002610) cDNA克隆 transcript variant 2

基因简介

Pyruvate dehydrogenase (PDH) is a mitochondrial multienzyme complex that catalyzes the oxidative decarboxylation of pyruvate and is one of the major enzymes responsible for the regulation of homeostasis of carbohydrate fuels in mammals. The enzymatic activity is regulated by a phosphorylation/dephosphorylation cycle. Phosphorylation of PDH by a specific pyruvate dehydrogenase kinase (PDK) results in inactivation. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jun 2013]

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