人 PDK2 (NM_001199899) cDNA克隆

基本信息

Accession: NM_001199899
基因名称: PDK2
基因别名: PDHK2; PDKII
基因描述: Homo sapiens pyruvate dehydrogenase kinase, isozyme 2 (PDK2), transcript variant 3, mRNA.
种属: Human
CDS区长度: 1032 (查看编码区序列)
翻译后氨基酸长度: 343 (查看氨基酸序列)
Transcript Variant: This variant (3) differs in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at an alternate start codon, compared to variant 1. The encoded isoform (2) has a distinct N-terminus and is shorter than isoform 1. Variants 2 and 3 encode the same isoform (2).

订购信息

产品编号 产品名称 载体 规格 价格
G110741 人 PDK2 (NM_001199899) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 PDK2 (NM_002611) cDNA克隆 transcript variant 1
人 PDK2 (NM_001199898) cDNA克隆 transcript variant 2
人 PDK2 (NM_001199899) cDNA克隆 transcript variant 3
人 PDK2 (NM_001199900) cDNA克隆 transcript variant 4

基因简介

This gene encodes a member of the pyruvate dehydrogenase kinase family. The encoded protein phosphorylates pyruvate dehydrogenase, down-regulating the activity of the mitochondrial pyruvate dehydrogenase complex. Overexpression of this gene may play a role in both cancer and diabetes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2010]

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