人 SUV39H1 (NM_001282166) cDNA克隆

Accession: NM_001282166
基因名称: SUV39H1
基因别名: MG44; KMT1A; SUV39H; H3-K9-HMTase 1
基因描述: Homo sapiens suppressor of variegation 3-9 homolog 1 (Drosophila) (SUV39H1), transcript variant 1, mRNA.
种属: Human
CDS区长度: 1272 (查看编码区序列)
翻译后氨基酸长度: 423 (查看氨基酸序列)
Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
产品编号 产品名称 载体 规格 价格
G110791 人 SUV39H1 (NM_001282166) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes an evolutionarily-conserved protein containing an N-terminal chromodomain and a C-terminal SET domain. The encoded protein is a histone methyltransferase that trimethylates lysine 9 of histone H3, which results in transcriptional gene silencing. Loss of function of this gene disrupts heterochromatin formation and may cause chromosome instability. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]