人 SUV39H1 (NM_003173) cDNA克隆

基本信息

Accession: NM_003173
基因名称: SUV39H1
基因别名: MG44; KMT1A; SUV39H; H3-K9-HMTase 1
基因描述: Homo sapiens suppressor of variegation 3-9 homolog 1 (Drosophila) (SUV39H1), transcript variant 2, mRNA.
种属: Human
CDS区长度: 1239 (查看编码区序列)
翻译后氨基酸长度: 412 (查看氨基酸序列)
Transcript Variant: This variant (2) differs in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at an alternate start codon, compared to variant 1. The encoded isoform (2) is shorter and has a distinct N-terminus, compared to isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G110790 人 SUV39H1 (NM_003173) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 SUV39H1 (NM_001282166) cDNA克隆 transcript variant 1
人 SUV39H1 (NM_003173) cDNA克隆 transcript variant 2

基因简介

This gene encodes an evolutionarily-conserved protein containing an N-terminal chromodomain and a C-terminal SET domain. The encoded protein is a histone methyltransferase that trimethylates lysine 9 of histone H3, which results in transcriptional gene silencing. Loss of function of this gene disrupts heterochromatin formation and may cause chromosome instability. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]

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