人 PDLIM2 (NM_176871) cDNA克隆

Accession: NM_176871
基因名称: PDLIM2
基因别名: SLIM; MYSTIQUE
基因描述: Homo sapiens PDZ and LIM domain 2 (mystique) (PDLIM2), transcript variant 1, mRNA.
种属: Human
CDS区长度: 1101 (查看编码区序列)
翻译后氨基酸长度: 366 (查看氨基酸序列)
Transcript Variant: This variant (1) represents the longest transcript and encodes isoform 1.
产品编号 产品名称 载体 规格 价格
G110145 人 PDLIM2 (NM_176871) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a member of the ALP subfamily of PDZ-LIM domain proteins. The encoded protein suppresses anchorage-dependent growth and promotes cell migration and adhesion through interactions with the actin cytoskeleton via the PDZ domain. The encoded protein is also a putative tumor suppressor protein, and decreased expression of this gene is associated with several malignancies including breast cancer and adult T-cell leukemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2011]