人 PDLIM2 (NM_021630) cDNA克隆

基本信息

Accession: NM_021630
基因名称: PDLIM2
基因别名: SLIM; MYSTIQUE
基因描述: Homo sapiens PDZ and LIM domain 2 (mystique) (PDLIM2), transcript variant 2, mRNA.
种属: Human
CDS区长度: 1809 (查看编码区序列)
翻译后氨基酸长度: 602 (查看氨基酸序列)
Transcript Variant: This variant (2) differs in both UTRs and in the 5' and 3' coding regions, compared to variant 1. The resulting isoform (2) has distinct N- and C-termini and is longer than isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G110144 人 PDLIM2 (NM_021630) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 PDLIM2 (NM_176871) cDNA克隆 transcript variant 1
人 PDLIM2 (NM_021630) cDNA克隆 transcript variant 2
人 PDLIM2 (NM_198042) cDNA克隆 transcript variant 3

基因简介

This gene encodes a member of the ALP subfamily of PDZ-LIM domain proteins. The encoded protein suppresses anchorage-dependent growth and promotes cell migration and adhesion through interactions with the actin cytoskeleton via the PDZ domain. The encoded protein is also a putative tumor suppressor protein, and decreased expression of this gene is associated with several malignancies including breast cancer and adult T-cell leukemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2011]

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