人 RNPS1 (NM_001286627) cDNA克隆

Accession: NM_001286627
基因名称: RNPS1
基因别名: E5.1
基因描述: Homo sapiens RNA binding protein S1, serine-rich domain (RNPS1), transcript variant 5, mRNA.
种属: Human
CDS区长度: 774 (查看编码区序列)
翻译后氨基酸长度: 257 (查看氨基酸序列)
Transcript Variant: This variant (5) lacks two alternate exons compared to variant 2. The resulting isoform (c) has shorter and distinct N- and C-termini compared to isoform a.
产品编号 产品名称 载体 规格 价格
G109432 人 RNPS1 (NM_001286627) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein binds to the mRNA and remains bound after nuclear export, acting as a nucleocytoplasmic shuttling protein. This protein contains many serine residues. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2013]