人 RNPS1 (NM_001286625) cDNA克隆

Accession: NM_001286625
基因名称: RNPS1
基因别名: E5.1
基因描述: Homo sapiens RNA binding protein S1, serine-rich domain (RNPS1), transcript variant 3, mRNA.
种属: Human
CDS区长度: 918 (查看编码区序列)
翻译后氨基酸长度: 305 (查看氨基酸序列)
Transcript Variant: This variant (3) differs in the 5' UTR compared to variant (2). Variants 1, 2, and 3 all encode the same isoform (a).
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G109430 人 RNPS1 (NM_001286625) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein binds to the mRNA and remains bound after nuclear export, acting as a nucleocytoplasmic shuttling protein. This protein contains many serine residues. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2013]