人 PSMA6 (NM_001282232) cDNA克隆

基本信息

Accession: NM_001282232
基因名称: PSMA6
基因别名: IOTA; p27K; PROS27
基因描述: Homo sapiens proteasome (prosome, macropain) subunit, alpha type, 6 (PSMA6), transcript variant 2, mRNA.
种属: Human
CDS区长度: 504 (查看编码区序列)
翻译后氨基酸长度: 167 (查看氨基酸序列)
Transcript Variant: This variant (2) uses an alternate splice junction at the 5' end of the first exon compared to variant 1. This difference causes translation initiation at a downstream AUG and results in an isoform (b) with a shorter N-terminus compared to isoform a. Variants 2 and 3 both encode the same isoform (b).

订购信息

产品编号 产品名称 载体 规格 价格
G108527 人 PSMA6 (NM_001282232) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 PSMA6 (NM_002791) cDNA克隆 transcript variant 1
人 PSMA6 (NM_001282232) cDNA克隆 transcript variant 2
人 PSMA6 (NM_001282233) cDNA克隆 transcript variant 3
人 PSMA6 (NM_001282234) cDNA克隆 transcript variant 4

基因简介

The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Multiple transcript variants encoding several different isoforms have been found for this gene. A pseudogene has been identified on the Y chromosome. [provided by RefSeq, Aug 2013]

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