人 PSMA1 (NM_002786) cDNA克隆

基本信息

Accession: NM_002786
基因名称: PSMA1
基因别名: NU; HC2; PROS30
基因描述: Homo sapiens proteasome (prosome, macropain) subunit, alpha type, 1 (PSMA1), transcript variant 2, mRNA.
种属: Human
CDS区长度: 792 (查看编码区序列)
翻译后氨基酸长度: 263 (查看氨基酸序列)
Transcript Variant: This variant (2) differs in the 5' UTR and 5' coding region, compared to variant 1. The encoded isoform (2), also known as the short isoform, has a shorter N-terminus compared to isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G103708 人 PSMA1 (NM_002786) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 PSMA1 (NM_148976) cDNA克隆 transcript variant 1
人 PSMA1 (NM_002786) cDNA克隆 transcript variant 2
人 PSMA1 (NM_001143937) cDNA克隆 transcript variant 3

基因简介

The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Jan 2009]

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