人 BID (NM_001244572) cDNA克隆

基本信息

Accession: NM_001244572
基因名称: BID
基因别名: FP497
基因描述: Homo sapiens BH3 interacting domain death agonist (BID), transcript variant 7, mRNA.
种属: Human
CDS区长度: 300 (查看编码区序列)
翻译后氨基酸长度: 99 (查看氨基酸序列)
Transcript Variant: This variant (7) lacks two alternate coding exons compared to variant 1, that causes a frameshift. This variant uses a downstream in-frame start-codon, so the encoded isoform 3 has a shorter N-terminus, as compared to isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G108047 人 BID (NM_001244572) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 BID (NM_197966) cDNA克隆 transcript variant 1
人 BID (NM_001196) cDNA克隆 transcript variant 2
人 BID (NM_197967) cDNA克隆 transcript variant 3
人 BID (NM_001244567) cDNA克隆 transcript variant 4
人 BID (NM_001244569) cDNA克隆 transcript variant 5
人 BID (NM_001244570) cDNA克隆 transcript variant 6
人 BID (NM_001244572) cDNA克隆 transcript variant 7

基因简介

This gene encodes a death agonist that heterodimerizes with either agonist BAX or antagonist BCL2. The encoded protein is a member of the BCL-2 family of cell death regulators. It is a mediator of mitochondrial damage induced by caspase-8 (CASP8); CASP8 cleaves this encoded protein, and the COOH-terminal part translocates to mitochondria where it triggers cytochrome c release. Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined. [provided by RefSeq, Jul 2008]

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