人 BID (NM_197966) cDNA克隆

Accession: NM_197966
基因名称: BID
基因别名: FP497
基因描述: Homo sapiens BH3 interacting domain death agonist (BID), transcript variant 1, mRNA.
种属: Human
CDS区长度: 726 (查看编码区序列)
翻译后氨基酸长度: 241 (查看氨基酸序列)
Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).
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G108042 人 BID (NM_197966) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a death agonist that heterodimerizes with either agonist BAX or antagonist BCL2. The encoded protein is a member of the BCL-2 family of cell death regulators. It is a mediator of mitochondrial damage induced by caspase-8 (CASP8); CASP8 cleaves this encoded protein, and the COOH-terminal part translocates to mitochondria where it triggers cytochrome c release. Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined. [provided by RefSeq, Jul 2008]