人 RASSF8 (NM_001164748) cDNA克隆

基本信息

Accession: NM_001164748
基因名称: RASSF8
基因别名: HOJ1; C12orf2
基因描述: Homo sapiens Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 (RASSF8), transcript variant 3, mRNA.
种属: Human
CDS区长度: 1260 (查看编码区序列)
翻译后氨基酸长度: 419 (查看氨基酸序列)
Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. Variants 1, 2 and 3 encode the same isoform (a).

订购信息

产品编号 产品名称 载体 规格 价格
G106426 人 RASSF8 (NM_001164748) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 RASSF8 (NM_001164746) cDNA克隆 transcript variant 1
人 RASSF8 (NM_001164747) cDNA克隆 transcript variant 2
人 RASSF8 (NM_001164748) cDNA克隆 transcript variant 3
人 RASSF8 (NM_007211) cDNA克隆 transcript variant 4

基因简介

This gene encodes a member of the Ras-assocation domain family (RASSF) of tumor suppressor proteins. This gene is essential for maintaining adherens junction function in epithelial cells and has a role in epithelial cell migration. It is a lung tumor suppressor gene candidate. A chromosomal translocation t(12;22)(p11.2;q13.3) leading to the fusion of this gene and the FBLN1 gene is found in a complex type of synpolydactyly. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2011]

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