人 RNASEH2B (NM_024570) cDNA克隆

Accession: NM_024570
基因名称: RNASEH2B
基因别名: AGS2; DLEU8
基因描述: Homo sapiens ribonuclease H2, subunit B (RNASEH2B), transcript variant 1, mRNA.
种属: Human
CDS区长度: 939 (查看编码区序列)
翻译后氨基酸长度: 312 (查看氨基酸序列)
Transcript Variant: This variant (1) represents the shorter transcript but encodes the longer isoform (1).
产品编号 产品名称 载体 规格 价格
G105918 人 RNASEH2B (NM_024570) cDNA克隆 pDONR223 2ug质粒 点击询价

RNase H2 is composed of a single catalytic subunit (A) and two non-catalytic subunits (B and C) and specifically degrades the RNA of RNA:DNA hybrids. The protein encoded by this gene is the non-catalytic B subunit of RNase H2, which is thought to play a role in DNA replication. Multiple transcript variants encoding different isoforms have been found for this gene. Defects in this gene are a cause of Aicardi-Goutieres syndrome type 2 (AGS2). [provided by RefSeq, Nov 2008]