The protein encoded by this gene is a B-cell-specific scaffold protein that functions in B-cell receptor-induced calcium mobilization from intracellular stores. This protein can also promote Lyn-mediated tyrosine phosphorylation of inositol 1,4,5-trisphosphate receptors. Polymorphisms in this gene are associated with susceptibility to systemic lupus erythematosus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]
人 BANK1 (NM_017935) cDNA克隆
| Accession: | NM_017935 |
|---|---|
| 基因名称: | BANK1 |
| 基因别名: | BANK |
| 基因描述: | Homo sapiens B-cell scaffold protein with ankyrin repeats 1 (BANK1), transcript variant 1, mRNA. |
| 种属: | Human |
| CDS区长度: | 2358 (查看编码区序列) |
| 翻译后氨基酸长度: | 785 (查看氨基酸序列) |
| Transcript Variant: | This variant (1) represents the longest transcript and encodes the longest isoform (1). |
| 人 BANK1 (NM_017935) cDNA克隆 | transcript variant 1 |
| 人 BANK1 (NM_001083907) cDNA克隆 | transcript variant 2 |
| 人 BANK1 (NM_001127507) cDNA克隆 | transcript variant 3 |
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