人 BANK1 (NM_001083907) cDNA克隆

Accession: NM_001083907
基因名称: BANK1
基因别名: BANK
基因描述: Homo sapiens B-cell scaffold protein with ankyrin repeats 1 (BANK1), transcript variant 2, mRNA.
种属: Human
CDS区长度: 2268 (查看编码区序列)
翻译后氨基酸长度: 755 (查看氨基酸序列)
Transcript Variant: This variant (2) uses an alternate exon at its 5' end, compared to variant 1, which produces a unique 5' UTR and causes translation initiation at a downstream start codon, compared to variant 1. The encoded isoform (2) is shorter at the N-terminus, compared to isoform 1.
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G104359 人 BANK1 (NM_001083907) cDNA克隆 pDONR223 2ug质粒 点击询价

The protein encoded by this gene is a B-cell-specific scaffold protein that functions in B-cell receptor-induced calcium mobilization from intracellular stores. This protein can also promote Lyn-mediated tyrosine phosphorylation of inositol 1,4,5-trisphosphate receptors. Polymorphisms in this gene are associated with susceptibility to systemic lupus erythematosus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]