人 NAE1 (NM_003905) cDNA克隆

基本信息

Accession: NM_003905
基因名称: NAE1
基因别名: HPP1; ula-1; APPBP1; A-116A10.1
基因描述: Homo sapiens NEDD8 activating enzyme E1 subunit 1 (NAE1), transcript variant 1, mRNA.
种属: Human
CDS区长度: 1605 (查看编码区序列)
翻译后氨基酸长度: 534 (查看氨基酸序列)
Transcript Variant: This variant (1) encodes the predominant isoform (a).

订购信息

产品编号 产品名称 载体 规格 价格
G104073 人 NAE1 (NM_003905) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 NAE1 (NM_003905) cDNA克隆 transcript variant 1
人 NAE1 (NM_001018159) cDNA克隆 transcript variant 2
人 NAE1 (NM_001018160) cDNA克隆 transcript variant 3
人 NAE1 (NM_001286500) cDNA克隆 transcript variant 4

基因简介

The protein encoded by this gene binds to the beta-amyloid precursor protein. Beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. In addition, the encoded protein can form a heterodimer with UBE1C and bind and activate NEDD8, a ubiquitin-like protein. This protein is required for cell cycle progression through the S/M checkpoint. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

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