人 PPP1R8 (NM_014110) cDNA克隆

基本信息

Accession: NM_014110
基因名称: PPP1R8
基因别名: ARD1; ARD-1; NIPP1; NIPP-1; PRO2047
基因描述: Homo sapiens protein phosphatase 1, regulatory subunit 8 (PPP1R8), transcript variant 1, mRNA.
种属: Human
CDS区长度: 1056 (查看编码区序列)
翻译后氨基酸长度: 351 (查看氨基酸序列)
Transcript Variant: This variant (1) is the shortest transcript but encodes the predominant and longest isoform (alpha). Isoform alpha contains protein phosphatase inhibitory actvity.

订购信息

产品编号 产品名称 载体 规格 价格
G103441 人 PPP1R8 (NM_014110) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 PPP1R8 (NM_014110) cDNA克隆 transcript variant 1
人 PPP1R8 (NM_138558) cDNA克隆 transcript variant 2
人 PPP1R8 (NM_002713) cDNA克隆 transcript variant 3

基因简介

This gene, through alternative splicing, encodes three different isoforms. Two of the protein isoforms encoded by this gene are specific inhibitors of type 1 serine/threonine protein phosphatases and can bind but not cleave RNA. The third protein isoform lacks the phosphatase inhibitory function but is a single-strand endoribonuclease comparable to RNase E of E. coli. This isoform requires magnesium for its function and cleaves specific sites in A+U-rich regions of RNA. [provided by RefSeq, Jul 2008]

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