人 DPH3 (NM_206831) cDNA克隆

Accession: NM_206831
基因名称: DPH3
基因别名: DESR1; DPH3A; KTI11; ZCSL2; DELGIP; DELGIP1
基因描述: Homo sapiens diphthamide biosynthesis 3 (DPH3), transcript variant 1, mRNA.
种属: Human
CDS区长度: 249 (查看编码区序列)
翻译后氨基酸长度: 82 (查看氨基酸序列)
Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
产品编号 产品名称 载体 规格 价格
G102737 人 DPH3 (NM_206831) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a CSL zinc finger-containing protein that is required for dipthamide biosynthesis. The encoded protein is necessary for the initial step in the modification of a histidine residue in elongation factor-2 to diphthamide. This modified residue is a target for ADP ribosylation by the bacterial toxins diphtheria toxin and Pseudomonas exotoxin A. Alternative splicing results in multiple transcript variants that encode the same isoform. [provided by RefSeq, Feb 2009]