人 ETF1 (NM_001282185) cDNA克隆

基本信息

Accession: NM_001282185
基因名称: ETF1
基因别名: ERF; RF1; ERF1; TB3-1; D5S1995; SUP45L1
基因描述: Homo sapiens eukaryotic translation termination factor 1 (ETF1), transcript variant 3, mRNA.
种属: Human
CDS区长度: 1272 (查看编码区序列)
翻译后氨基酸长度: 423 (查看氨基酸序列)
Transcript Variant: This variant (3) uses an alternate 5' exon structure, and thus differs in the 5' UTR and 5' coding region, compared to variant 1. These differences cause translation initiation at an alternate AUG and result in an isoform (3) with a shorter and distinct N-terminus, compared to isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G101689 人 ETF1 (NM_001282185) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 ETF1 (NM_004730) cDNA克隆 transcript variant 1
人 ETF1 (NM_001256302) cDNA克隆 transcript variant 2
人 ETF1 (NM_001282185) cDNA克隆 transcript variant 3

基因简介

This gene encodes a class-1 polypeptide chain release factor. The encoded protein plays an essential role in directing termination of mRNA translation from the termination codons UAA, UAG and UGA. This protein is a component of the SURF complex which promotes degradation of prematurely terminated mRNAs via the mechanism of nonsense-mediated mRNA decay (NMD). Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 6, 7, and X. [provided by RefSeq, Aug 2013]

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