人 ETF1 (NM_001256302) cDNA克隆

基本信息

Accession: NM_001256302
基因名称: ETF1
基因别名: ERF; RF1; ERF1; TB3-1; D5S1995; SUP45L1
基因描述: Homo sapiens eukaryotic translation termination factor 1 (ETF1), transcript variant 2, mRNA.
种属: Human
CDS区长度: 1215 (查看编码区序列)
翻译后氨基酸长度: 404 (查看氨基酸序列)
Transcript Variant: This variant (2) uses an alternate 5' exon structure, and thus differs in the 5' UTR and 5' coding region, compared to variant 1. These differences cause translation initiation at a downstream AUG and result in an isoform (2) with a shorter N-terminus, compared to isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G101688 人 ETF1 (NM_001256302) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 ETF1 (NM_004730) cDNA克隆 transcript variant 1
人 ETF1 (NM_001256302) cDNA克隆 transcript variant 2
人 ETF1 (NM_001282185) cDNA克隆 transcript variant 3

基因简介

This gene encodes a class-1 polypeptide chain release factor. The encoded protein plays an essential role in directing termination of mRNA translation from the termination codons UAA, UAG and UGA. This protein is a component of the SURF complex which promotes degradation of prematurely terminated mRNAs via the mechanism of nonsense-mediated mRNA decay (NMD). Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 6, 7, and X. [provided by RefSeq, Aug 2013]

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