人 IL1RN (NM_173843) cDNA克隆

基本信息

Accession: NM_173843
基因名称: IL1RN
基因别名: DIRA; IRAP; IL1F3; IL1RA; MVCD4; IL-1RN; IL-1ra; IL-1ra3; ICIL-1RA
基因描述: Homo sapiens interleukin 1 receptor antagonist (IL1RN), transcript variant 4, mRNA.
种属: Human
CDS区长度: 432 (查看编码区序列)
翻译后氨基酸长度: 143 (查看氨基酸序列)
Transcript Variant: This variant (4) contains a distinct internal exon compared to variant 2. This results in translation from a downstream start codon, and an isoform (4) that has a shorter N-terminus, as compared to the longest isoform (2).

订购信息

产品编号 产品名称 载体 规格 价格
G100308 人 IL1RN (NM_173843) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 IL1RN (NM_173842) cDNA克隆 transcript variant 1
人 IL1RN (NM_173841) cDNA克隆 transcript variant 2
人 IL1RN (NM_000577) cDNA克隆 transcript variant 3
人 IL1RN (NM_173843) cDNA克隆 transcript variant 4

基因简介

The protein encoded by this gene is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1, alpha (IL1A) and interleukin 1, beta (IL1B), and modulates a variety of interleukin 1 related immune and inflammatory responses. This gene and five other closely related cytokine genes form a gene cluster spanning approximately 400 kb on chromosome 2. A polymorphism of this gene is reported to be associated with increased risk of osteoporotic fractures and gastric cancer. Four alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]

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