人 IL1RN (NM_000577) cDNA克隆

基本信息

Accession: NM_000577
基因名称: IL1RN
基因别名: DIRA; IRAP; IL1F3; IL1RA; MVCD4; IL-1RN; IL-1ra; IL-1ra3; ICIL-1RA
基因描述: Homo sapiens interleukin 1 receptor antagonist (IL1RN), transcript variant 3, mRNA.
种属: Human
CDS区长度: 480 (查看编码区序列)
翻译后氨基酸长度: 159 (查看氨基酸序列)
Transcript Variant: This variant (3) lacks an inframe coding segment, as compared to variant 2. The resulting isoform (3) lacks an internal region, as compared to the longest isoform (2).

订购信息

产品编号 产品名称 载体 规格 价格
G100305 人 IL1RN (NM_000577) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 IL1RN (NM_173842) cDNA克隆 transcript variant 1
人 IL1RN (NM_173841) cDNA克隆 transcript variant 2
人 IL1RN (NM_000577) cDNA克隆 transcript variant 3
人 IL1RN (NM_173843) cDNA克隆 transcript variant 4

基因简介

The protein encoded by this gene is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1, alpha (IL1A) and interleukin 1, beta (IL1B), and modulates a variety of interleukin 1 related immune and inflammatory responses. This gene and five other closely related cytokine genes form a gene cluster spanning approximately 400 kb on chromosome 2. A polymorphism of this gene is reported to be associated with increased risk of osteoporotic fractures and gastric cancer. Four alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]

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