人 NUP153 (NM_005124) cDNA克隆

Accession: NM_005124
基因名称: NUP153
基因别名: N153; HNUP153
基因描述: Homo sapiens nucleoporin 153kDa (NUP153), transcript variant 2, mRNA.
种属: Human
CDS区长度: 4428 (查看编码区序列)
翻译后氨基酸长度: 1475 (查看氨基酸序列)
Transcript Variant: This variant (2) lacks an alternate in-frame exon in the 5' coding region compared to variant 1. It encodes isoform 2 which is shorter than isoform 1.
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G168114 人 NUP153 (NM_005124) cDNA克隆 pDONR223 2ug质粒 点击询价

Nuclear pore complexes regulate the transport of macromolecules between the nucleus and cytoplasm. They are composed of at least 100 different polypeptide subunits, many of which belong to the nucleoporin family. Nucleoporins are glycoproteins found in nuclear pores and contain characteristic pentapeptide XFXFG repeats as well as O-linked N-acetylglucosamine residues oriented towards the cytoplasm. The protein encoded by this gene has three distinct domains: a N-terminal region containing a pore targeting and an RNA-binding domain domain, a central region containing multiple zinc finger motifs, and a C-terminal region containing multiple XFXFG repeats. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, May 2013]