人 BCLAF1 (NM_001077440) cDNA克隆

Accession: NM_001077440
基因名称: BCLAF1
基因别名: BTF; bK211L9.1
基因描述: Homo sapiens BCL2-associated transcription factor 1 (BCLAF1), transcript variant 2, mRNA.
种属: Human
CDS区长度: 2610 (查看编码区序列)
翻译后氨基酸长度: 869 (查看氨基酸序列)
Transcript Variant: This variant (2), also known as btfS, lacks an alternate in-frame exon, compared to variant 1. The resulting protein (isoform 2) is shorter than isoform 1.
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G167889 人 BCLAF1 (NM_001077440) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a transcriptional repressor that interacts with several members of the BCL2 family of proteins. Overexpression of this protein induces apoptosis, which can be suppressed by co-expression of BCL2 proteins. The protein localizes to dot-like structures throughout the nucleus, and redistributes to a zone near the nuclear envelope in cells undergoing apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]