人 NCOR2 (NM_001206654) cDNA克隆

基本信息

Accession: NM_001206654
基因名称: NCOR2
基因别名: SMRT; TRAC; CTG26; SMRTE; TRAC1; N-CoR2; TNRC14; TRAC-1; SMAP270; SMRTE-tau
基因描述: Homo sapiens nuclear receptor corepressor 2 (NCOR2), transcript variant 3, mRNA.
种属: Human
CDS区长度: 7515 (查看编码区序列)
翻译后氨基酸长度: 2504 (查看氨基酸序列)
Transcript Variant: This variant (3) has multiple difference in the coding region, but maintains the reading frame, compared to variant 1. The resulting isoform (3) has the same N- and C-termini but is shorter than isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G167770 人 NCOR2 (NM_001206654) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 NCOR2 (NM_006312) cDNA克隆 transcript variant 1
人 NCOR2 (NM_001077261) cDNA克隆 transcript variant 2
人 NCOR2 (NM_001206654) cDNA克隆 transcript variant 3

基因简介

This gene encodes a nuclear receptor co-repressor that mediates transcriptional silencing of certain target genes. The encoded protein is a member of a family of thyroid hormone- and retinoic acid receptor-associated co-repressors. This protein acts as part of a multisubunit complex which includes histone deacetylases to modify chromatin structure that prevents basal transcriptional activity of target genes. Aberrant expression of this gene is associated with certain cancers. Alternate splicing results in multiple transcript variants encoding different isoforms.[provided by RefSeq, Apr 2011]

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