人 NCOR1 (NM_001190440) cDNA克隆

基本信息

Accession: NM_001190440
基因名称: NCOR1
基因别名: N-CoR; TRAC1; N-CoR1; hN-CoR
基因描述: Homo sapiens nuclear receptor corepressor 1 (NCOR1), transcript variant 3, mRNA.
种属: Human
CDS区长度: 7014 (查看编码区序列)
翻译后氨基酸长度: 2337 (查看氨基酸序列)
Transcript Variant: This variant (3) differs in the 5' UTR and has multiple differences in the coding region but maintains the reading frame, compared to variant 1. This variant encodes isoform 3, which is shorter than isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G167767 人 NCOR1 (NM_001190440) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 NCOR1 (NM_006311) cDNA克隆 transcript variant 1
人 NCOR1 (NM_001190438) cDNA克隆 transcript variant 2
人 NCOR1 (NM_001190440) cDNA克隆 transcript variant 3

基因简介

This gene encodes a protein that mediates ligand-independent transcription repression of thyroid-hormone and retinoic-acid receptors by promoting chromatin condensation and preventing access of the transcription machinery. It is part of a complex which also includes histone deacetylases and transcriptional regulators similar to the yeast protein Sin3p. This gene is located between the Charcot-Marie-Tooth and Smith-Magenis syndrome critical regions on chromosome 17. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 17 and 20.[provided by RefSeq, Jun 2010]

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