人 NCOR1 (NM_001190438) cDNA克隆

基本信息

Accession: NM_001190438
基因名称: NCOR1
基因别名: N-CoR; TRAC1; N-CoR1; hN-CoR
基因描述: Homo sapiens nuclear receptor corepressor 1 (NCOR1), transcript variant 2, mRNA.
种属: Human
CDS区长度: 2745 (查看编码区序列)
翻译后氨基酸长度: 914 (查看氨基酸序列)
Transcript Variant: This variant (2) has multiple differences compared to variant 1, one of which results in a translational frameshift. The resulting protein (isoform 2) has a distinct C-terminus and is shorter than isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G167766 人 NCOR1 (NM_001190438) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 NCOR1 (NM_006311) cDNA克隆 transcript variant 1
人 NCOR1 (NM_001190438) cDNA克隆 transcript variant 2
人 NCOR1 (NM_001190440) cDNA克隆 transcript variant 3

基因简介

This gene encodes a protein that mediates ligand-independent transcription repression of thyroid-hormone and retinoic-acid receptors by promoting chromatin condensation and preventing access of the transcription machinery. It is part of a complex which also includes histone deacetylases and transcriptional regulators similar to the yeast protein Sin3p. This gene is located between the Charcot-Marie-Tooth and Smith-Magenis syndrome critical regions on chromosome 17. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 17 and 20.[provided by RefSeq, Jun 2010]

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