人 TNFRSF8 (NM_001281430) cDNA克隆

基本信息

Accession: NM_001281430
基因名称: TNFRSF8
基因别名: CD30; Ki-1; D1S166E
基因描述: Homo sapiens tumor necrosis factor receptor superfamily, member 8 (TNFRSF8), transcript variant 3, mRNA.
种属: Human
CDS区长度: 1452 (查看编码区序列)
翻译后氨基酸长度: 483 (查看氨基酸序列)
Transcript Variant: This variant (3) has multiple differences, compared to variant 1. These differences result in a distinct 5' UTR and cause translation initiation at a downstream start codon, compared to variant 1. The encoded protein (isoform 3) is shorter than isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G167678 人 TNFRSF8 (NM_001281430) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 TNFRSF8 (NM_001243) cDNA克隆 transcript variant 1
人 TNFRSF8 (NM_001281430) cDNA克隆 transcript variant 3

基因简介

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB. This receptor is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]

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