人 CD163 (NM_203416) cDNA克隆

基本信息

Accession: NM_203416
基因名称: CD163
基因别名: M130; MM130
基因描述: Homo sapiens CD163 molecule (CD163), transcript variant 2, mRNA.
种属: Human
CDS区长度: 3366 (查看编码区序列)
翻译后氨基酸长度: 1121 (查看氨基酸序列)
Transcript Variant: This variant (2), also known as short tail variant, uses an alternate acceptor splice site at the penultimate exon compared to variant 1. This results in a frame-shift, and an isoform (b) with a shorter and distinct C-terminus compared to isoform a.

订购信息

产品编号 产品名称 载体 规格 价格
G167357 人 CD163 (NM_203416) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 CD163 (NM_004244) cDNA克隆 transcript variant 1
人 CD163 (NM_203416) cDNA克隆 transcript variant 2

基因简介

The protein encoded by this gene is a member of the scavenger receptor cysteine-rich (SRCR) superfamily, and is exclusively expressed in monocytes and macrophages. It functions as an acute phase-regulated receptor involved in the clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages, and may thereby protect tissues from free hemoglobin-mediated oxidative damage. This protein may also function as an innate immune sensor for bacteria and inducer of local inflammation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011]

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